What Causes Obesity? More Science Points to the Brain

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Michael Smith struggled with obesity and food cravings for much of his life. Doctors are now beginning to consider obesity as a brain disorder, with brain-based treatments being developed to help patients. Research suggests that people with obesity may have broken circuits in their brain, leading to impaired gut-brain pathways, decreased responses after meals, and altered appetite control. Genetics play a role, but the increase in ultra-processed foods in the food supply is also a significant factor. Studies have shown that ultra-processed foods can lead to overeating and weight gain, while also reprogramming the brain to dislike healthy foods. The brain’s negative adaptations to modern food pose challenges for reversing obesity.

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