disease

The Integrated Health Information Platform gathers almost real-time data of disease incidence and creates analysed reports to investigate potential outbreaks. Source link

Biomed Res Int. 2021 Mar 26;2021:5538535. doi: 10.1155/2021/5538535. eCollection 2021.ABSTRACTTumor necrosis factor alpha (TNF-α) plays a critical role in the progression of inflammation and affects the cells of the synovial membrane.…

Altered perivascular fibroblast activity precedes ALS disease onset Source link

SOUTH SAN FRANCISCO, Calif.--(BUSINESS WIRE)--Genentech, a member of the Roche Group (SIX: RO, ROG; OTCQX: RHHBY), today announced new Ocrevus® (ocrelizumab) analyses supporting its significant benefit on disease progression in…

UC researchers present findings that could give patients with Pompe disease a better quality of life Credit: University of Cincinnati Rare diseases are sometimes the most difficult to treat because of a lack of research and fewer…

Researchers from Kumamoto University have found that the anti-diabetic drug metformin significantly prolongs the survival of mice in a model that simulates the pathology of non-diabetic chronic kidney disease (ND-CKD) by ameliorating…

A new study reveals those who score high on the personality traits associated with neuroticism are at higher risk of developing Parkinson's disease. Source link

ACS Chem Neurosci. 2021 Apr 14. doi: 10.1021/acschemneuro.1c00184. Online ahead of print.ABSTRACTSince 2002, no clinical candidate against Alzheimer's disease has reached the market; hence, an effective therapy is urgently needed. We…

Credit: Radiological Society of North America OAK BROOK, Ill. – A deep learning algorithm accurately predicts the risk of death from cardiovascular disease using information from low-dose CT exams performed for lung cancer…

Fecal dipeptidyl peptidase-4 may be used as a noninvasive biomarker in patients with inflammatory bowel disease, according to research published in Clinical and Translational Gastroenterology.“Although the diagnosis of IBD is still a…

Behçet’s Syndrome (BS) may present with different neurological problems, related either directly (primary) or indirectly (secondary) to BS. Primary neurological involvement is named as neuro-Behcet’s syndrome (NBS), and its two major…

Delayed orthostatic hypotension in Parkinson’s disease Source link

We thank Dr. Sioka et al. for their positive comments about our article1 showing a high risk of major adverse cardiovascular events after acute ischemic stroke. They also summarized the results of their study on myocardial perfusion…

(MedPage Today) -- Despite higher utilization of immunomodulators and biologics, perianal Crohn's disease (PCD), especially the severe phenotype, is associated with poor outcomes, a large population-based study from Israel found. Data…

In their large population-based study, Sposato et al.1 reported that ischemic stroke was independently associated with a higher risk of a subsequent major adverse cardiovascular event, such as myocardial infarction, congestive heart…

Using a propensity-matched cohort of >20,000 patients with acute ischemic stroke and >70,000 matched nonstroke individuals, Dr. Sposato et al. observed a 4-fold higher odds of major cardiac adverse events among patients with recent…

Objective To determine whether CT-based cerebral small vessel disease (SVD) biomarkers are associated with 6-month functional outcome after intracerebral hemorrhage (ICH) and whether these biomarkers improve the performance of the…

Objective We sought to identify an abbreviated test of impaired olfaction amenable for use in busy clinical environments in prodromal (isolated REM sleep behavior disorder ) and manifest Parkinson disease (PD). Methods Eight hundred…

New findings suggest dietary modification and new molecular targets may control common genetic disorder Credit: UT Southwestern Medical Center DALLAS – April 13, 2021 – A chemical modification of RNA that can be…

In a small phase 2 trial, GM-CSF/sargramostim provided measurable disease-modifying and memory-enhancing benefits in patients with mild-to-moderate Alzheimer's disease. Medscape Medical News Source link