Gut-friendly psychobiotics could brighten moods and fight depression

Researchers reviewed the use of psychobiotics for treating depression through restoring microbial balance and regulating the microbiome-gut-brain axis. Dysbiosis, or gut microbiome imbalance, can affect the gut-brain axis, leading to microbial alterations that contribute to depression. Psychobiotics have positive effects on the gut barrier, immune responses, and hormone regulation, making them a potential treatment for depression, especially in treatment-resistant cases. The gut-brain axis plays a crucial role in depressive disorders, with a link between intestinal microbes, inflammatory responses, and brain function. Probiotic gut microbes and their metabolites impact mental health through various mechanisms, with clinical evidence supporting their role in reducing depressive symptoms.

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