Deciphering how amino acids control cell growth and autophagy in yeast

Amino acids are essential building blocks in the human body, critical for the production of proteins and various cellular functions. TORC1, a master protein regulator, is switched on with the presence of amino acids, causing cells to grow and proteins to be made. Researchers from Osaka University discovered that the amino acid cysteine is a key factor in triggering TORC1 activation in yeast, leading to the synthesis of proteins and lipids. This study also found that other amino acids use different pathways to affect TORC1. Understanding this process may have implications for treating diseases like cancer, diabetes, and dementia caused by faulty TORC1 function.

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