Researchers found key driver genes linked to ozone and fine particulate matter exposure in patients with asthma. Six genes were identified for ozone exposure and three for fine particulate matter exposure, with the FGL2 gene appearing in both types of pollution. Poor air quality triggers asthma exacerbations. The study involved 167 patients with asthma in the New York metropolitan area, with most patients being white or Latino. Key driver genes for asthma and air pollution encode proteins involved in inflammation and pro-allergic responses. The study highlights the distinctive pro-inflammatory response to air pollution in individuals with asthma.
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Nasal key driver genes linked to ozone, fine particulate matter exposure in asthma
