BET inhibitors combined with JAK inhibitors well-tolerated with myelofibrosis

The BET inhibitor BMS986158 has shown promising preliminary data of potential disease modification in patients with intermediate- or high-risk myelofibrosis when used in combination with ruxolitinib and fedratinib. The phase…

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Carvykti CAR-T gets warning label

The Food and Drug Administration has issued a new warning label for Legend Biotech and Janssen’s myeloma CAR-T, Carvykti or cilta-cel, due to the occurrence of some secondary blood cancers…

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Europe suspends hundreds of generic drugs over serious data concerns

The European Medicines Agency suspended the marketing authorizations of 365 generic drugs after concerns were raised about the reliability of the testing conducted by Synapse Labs, a contract research organization…

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Predicting Alzheimer’s dementia in oldest of the old

A new study indicates that the severity of amyloid deposition in the brain, rather than just age, may be a key factor in determining who will benefit from new anti-amyloid…

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Sales of emergency contraception estimated to rise after the New Year holiday

A study published in The BMJ found that sales of emergency contraception in the US rise by around 10% in the week after the New Year holiday. Other holidays such…

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Protect Your Mental Health This Holiday Season

The content discusses the holiday blues and ways to protect your mental health during the festive season. WebMD's Chief Medical Officer John Whyte explains the symptoms of holiday blues, strategies…

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Opioid Agonist Therapy Underused, Data Suggest

A study in Ontario, Canada found that only 4.1% of hospital visits for opioid use disorder (OUD) resulted in community-based initiation of opioid agonist therapy (OAT) within 7 days of…

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Sleep Loss May Reduce Positivity, Increase Your Risk Of Anxiety

A new study by the American Psychological Association found that lack of proper sleep reduces positivity and increases the risk for anxiety symptoms in individuals. The study looked at data…

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Environmental Metal Exposure Associated with Increased Breast Cancer Risk

A study has found that environmental exposure to metals is associated with an increased risk of breast cancer. Researchers found higher levels of metals such as cadmium, chromium, and lead…

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How to Ensure Health Equity Isn’t Just a Buzzword

Health equity in the U.S. healthcare system is a serious issue, with many patients lacking necessary resources or facing discrimination based on factors like income, race, ethnicity, sexual orientation, or…

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