A cohort study of 16,251 Korean women with breast cancer showed that those aged 35 and younger had a higher risk for developing contralateral breast cancer compared to older women. The study revealed that younger women also had higher 10-year cumulative incidence of breast cancer. The risk for contralateral breast cancer differed based on the subtype of breast cancer, with hormone receptor-positive/ERBB2-negative subtype showing a continuous increase in risk over time for both younger and older women. The researchers believe these findings could be valuable for physicians and assist in the decision-making process for patients considering contralateral prophylactic mastectomy, but further research with larger sample sizes is needed to confirm and validate the results.
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