A study published in the Journal of the American Medical Association Network Open found that home-based walking exercise is associated with greater improvement in 6-minute walk distance in patients with peripheral artery disease (PAD) compared to supervised treadmill exercise. The study analyzed data from 5 randomized clinical trials and found that home-based walking exercise was more effective in improving 6MW distance and walking impairment questionnaire (WIQ) scores, although the differences in WIQ scores did not reach statistical significance. The investigators recommend home-based walking exercise as a first-line therapy for walking limitations in PAD. The study had limitations, including the lack of statistical power for WIQ measures.
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