Atopic dermatitis (AD) causes redness, discolored, dryness, and itch and severity is determined by body surface affected and color of the affected area. Topical treatments with coal tar, steroid creams, calcineurin inhibitors, and new medications like crisaborole can help control itching and inflammation. Phototherapy is an option for large areas of AD. Systemic drugs like cyclosporine, and off-label medicines like Azathioprine and Methotrexate can be used for severe cases, but may have serious side effects. The FDA approved the biologic drug dupilumab (Dupixent) for moderate to severe AD in 2017, which has been a game changer for the treatment of AD. New treatments like Dupixent have improved the outlook and quality of life for people with AD.
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