Semaglutide Treatment Exhibits Cardioprotective Utility Across HbA1c Levels

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A study published in the European Heart Journal found that semaglutide, a medication for type 2 diabetes, reduces major adverse cardiovascular events (MACEs) and improves metabolic outcomes compared to a placebo, regardless of baseline glycated hemoglobin (HbA1c) levels. The study analyzed data from two randomized controlled trials and included 6480 participants with type 2 diabetes and cardiovascular disease or high cardiovascular risk. Semaglutide was associated with a lower risk of MACEs and consistent reductions in HbA1c and body weight, regardless of baseline HbA1c levels. The researchers concluded that semaglutide benefits were consistent across all HbA1c levels.

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