Risk factors for faster aging in the brain revealed in new study

A study published in Nature Communications examined the genetic and modifiable factors affecting vulnerable brain regions in over 40,000 UK Biobank participants over 45 years old. Researchers identified a network of brain regions that degenerate earlier and are susceptible to Alzheimer’s disease. They studied 161 risk factors for dementia and categorized them into 15 groups, including blood pressure, diabetes, alcohol, and pollution. Diabetes, air pollution, and alcohol were found to be the most harmful factors. Genetic variations in specific regions were also associated with cardiovascular diseases and neurological conditions. This research provides valuable insights for preventing dementia and developing targeted interventions.

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