Patient-Reported Outcomes Important in Cutaneous GVHD: Study

A longitudinal study involving 436 patients with chronic GVHD found that patients with sclerotic and combination disease had worse symptoms and quality-of-life impairment compared to those with epidermal disease. The study used two validated patient-reported outcome tools to measure these factors. PROs were also found to predict non-relapse mortality for all three disease subtypes, indicating their potential use in risk stratification and treatment decisions. The study highlighted the importance of patient-reported outcomes in assessing chronic GVHD, especially for patients with sclerotic disease. Future research will focus on determining the most clinically relevant PROs for patients with chronic GVHD.

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