Researchers have found that a specific bacteria species in the gut, Akkermansia muciniphila, can strip sugar from antibodies and make them unrecognizable to the immune system. This process may contribute to the development of IgA nephropathy, an autoimmune kidney disease. The bacteria alters the antibodies in a way that leads to kidney inflammation and potential failure. Further research is needed to understand the chemical reactions involved and the potential for developing targeted treatments. This discovery could have implications for other autoimmune diseases and highlights the complex relationship between gut microbiota and human health.
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Gut bacteria may contribute to kidney autoimmunity, study finds
