Blood Donor’s Diet May Trigger Allergic Reactions In Recipients: Study

A study found a link between a donor’s pre-donation diet and allergic transfusion reactions (ATRs) in recipients, especially children. ATRs can occur in up to 2% of blood transfusions, posing life-threatening risks. Researchers discovered allergens from a donor’s pre-donation diet could induce ATRs in recipients with food allergies. The study involved blood samples from children with egg, wheat, or milk allergies, testing basophil activation after exposure to donor serum. Results showed increased basophil levels in patients exposed to donor serum containing allergens they were allergic to. Further research is needed, but the findings suggest potential ways to predict and prevent ATRs in the future.

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