Transgender Males Ovulate Despite Amenorrhoea

A study found that one third of 52 transmasculine individuals receiving testosterone and scheduled for oophorectomy ovulated, highlighting the importance of contraception for sexually active individuals. The study involved evaluating the ovaries of these individuals for signs of ovulatory activity, with 17 out of 52 displaying recent ovulation. The researchers noted that amenorrhea does not necessarily mean anovulation in transmasculine individuals on testosterone therapy. The study’s limitations included its observational design and lack of a control group. Funding was provided by the European Research Council and Novo Nordisk Foundation. The findings were published in Cell Reports Medicine.

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