STAT publishes selected Letters to the Editor in response to First Opinion essays to foster discussion on challenging issues. Contributors reflect on aging and cognition, the benefits of a polypill for cardiovascular disease prevention, and Medicare coverage for Puerto Ricans. One physician acknowledges individual aging experiences while another stresses the importance of assessing studies comparing polypills with usual care. Additionally, a reader clarifies the impact of the Inflation Reduction Act on drug costs for Puerto Ricans. These diverse perspectives highlight the need for informed debate on healthcare topics.
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