Cytisine, a potential drug therapy for smoking cessation, was found to double the chances of successful smoking cessation compared to placebo in a study published in Addiction. Researchers conducted a systematic review and meta-analysis of 12 randomized controlled trials (RCTs) comparing cytisine with placebo, nicotine replacement therapy (NRT), and varenicline alongside behavioral therapies for smoking cessation. The findings showed that cytisine was more effective than placebo, with a low incidence of non-serious adverse events. However, the study noted limitations such as a small sample size and heterogeneity across studies. More research is needed to assess the cost-effectiveness and economic evaluations of community-based tobacco dependence interventions.
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Patients Are Twice as Likely to Quit Smoking with Cytisine
