A review of 45 articles with a total of 28,183 participants focused on the correlation between pain, function, and disease progression in patients with first carpometacarpal (CMC) osteoarthritis (OA). The study found that imaging results and radiography-based staging systems had significant associations with pain but lacked strong correlations with functional status or disease progression. Osteophytes were identified as a significant indicator of pain, but radiographic findings alone showed inconsistent associations with pain. The study also found limited connections between imaging findings and the longitudinal progression of first CMC OA. The review concluded that improved imaging techniques are needed to help physicians manage patients with this condition.
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