Extracranial Surgery, Anesthesia After TBI Tied to Poorer Clinical Outcomes

A study published in JAMA Surgery found that extracranial surgery and anesthesia are linked to worsened cognitive and functional outcomes after traumatic brain injury (TBI). The study, based on data from TRACK-TBI, included 1835 participants with TBI. The researchers found that patients who underwent extracranial surgery had significantly worse outcomes at 2 weeks and 6 months after injury compared to those who did not require surgery. Patients with moderate to severe TBI had the worst outcomes. The researchers suggest that TBI should be considered a nonmodifiable patient factor that increases the risk for postoperative neurocognitive disorders. The study authors disclosed affiliations with biotech, pharmaceutical, and/or device companies.

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