Cognitive benefits seen two years after bariatric surgery

A recent study found that bariatric surgery is associated with cognitive benefits two years after the surgery. The study involved 133 participants with severe obesity, eligible for Roux-en-Y gastric bypass. At 24 months after surgery, global cognition was at least 20 percent higher in 42.9 percent of participants. Inflammatory markers were lower, fewer patients used antihypertensives, and patients had lower depressive symptoms and greater physical activity. Brain structure and perfusion were lower in most regions after surgery, with no change in hippocampal and white matter volume. The study provides new information on longer-term outcomes, although underlying mechanisms remain unsolved. The results were published in JAMA Network Open.

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