A study published in the European Journal of Heart Failure found that the risk of cardiovascular death and hospitalization due to heart failure is reduced in patients with low systolic blood pressure (SBP) when they are receiving higher doses of heart failure medications. The study used data from the Swedish Heart Failure Registry, and results showed that patients with lower SBP and less than maximal doses of heart failure medications had an increased risk of adverse outcomes. However, those with higher or increasing doses of medication had a reduced risk, suggesting that hypotension is less harmful when associated with optimized medication dosing.
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Effects of Hypotension in HFrEF Partially Mitigated by HF Medication Optimization
