Research at University of California San Diego School of Medicine found a connection between cellular metabolism and depression, and how different genders are impacted. They say that tools that could help stratify individuals based on their risk of becoming suicidal could help save lives. They analyzed the blood of 99 participants with treatment-refractory depression and suicidal ideation, and found they could identify patients at the greatest risk based on five metabolites in males and females. Mitochondrial dysfunction also occurs when people have suicidal ideation, and they hope that by monitoring these metabolic markers, it could lead to finding new drugs that target this dysfunction and save lives.
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