Guidance for Managing Patients With Drug Reaction With Eosinophilia and Systemic Symptoms

An international panel of experts used the Delphi method to develop consensus on guidance for managing adults with drug reaction with eosinophilia and systemic symptoms (DRESS) and published their recommendations in JAMA Dermatology. The panel identified 7 categories to address and conducted a literature review to draft statements for consideration. After a 2-round Delphi exercise with 54 experts from 19 countries, the panel reached consensus on 93 statements. The recommendations include the use of corticosteroids, regular follow-up consultations for the first 6 months, and consideration of treatment options for corticosteroid-refractory DRESS. The experts acknowledged study limitations and emphasized the importance of the consensus in guiding optimal patient management.

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