Reducing risk of bone fracture in people with rare genetic disorder

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A recent study conducted by researchers from McGill University and Shriners Hospitals for Children Canada used the Canadian Light Source to investigate bone structure in mice with Marfan Syndrome (MFS). The study aimed to better understand the bones of individuals with MFS, who are at a higher risk of fractures due to decreased bone density. The research found that bones affected by MFS have smaller pores, potentially impacting mechanosensation and increasing fracture risk. Understanding this mechanism could help develop strategies to reduce fracture risk not only for individuals with MFS but also for those with conditions like osteoporosis and rheumatoid arthritis.

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