Dynamic Troponin Changes Unreliable for MI in Acute Stroke

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The PRAISE study found that dynamic changes in high-sensitivity cardiac troponin levels in patients with acute ischemic stroke are not helpful in identifying myocardial infarction or distinguishing it from other types of acute myocardial injury. However, high levels of troponin on admission were associated with atherosclerotic heart attacks in this patient population. The study also revealed a high rate of type 1 heart attacks in these patients, suggesting that many strokes could be caused by unrecognized heart attacks. Further research is needed to determine the best approach to evaluating and treating heart disease in stroke patients with elevated troponin levels.

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