Rhinovirus infections in children with a nascent type 2 inflammatory signature may increase the risk for asthma, according to a study presented at the American College of Allergy, Asthma & Immunology Annual Scientific Meeting. More than a quarter of children with refractory wheeze were positive for rhinovirus without symptoms, indicating indolent infections. The study found no evidence of systemic type 2 inflammatory disease in these children, but they did show increased airway eosinophilia. This research suggests that indolent rhinovirus infections may predict asthma development and calls for reconsidering standard corticosteroid therapy in these cases.ongoing research is exploring the implications of silent rhinovirus-associated bronchoalveolitis in children.
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