Estrogen’s role in female binge drinking revealed by preclinical study

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Estrogen hormone in females increases binge drinking behavior, leading to excessive alcohol consumption in a short period. Studies show that estrogen levels correlate with heightened alcohol consumption in females. This behavior is driven by the hormone binding to cell-surface receptors in the brain, resulting in rapid neural activity that triggers binge drinking. Understanding this mechanism could lead to novel treatments for alcohol use disorder, especially in women who are more susceptible to its negative health effects. Targeting the estrogen-receptor system in the brain holds promise for reducing alcohol consumption during hormonal surges, offering a potential new approach for treating alcohol use disorder.

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