New study assesses long-term risk of invasive breast cancer after pre-invasive disease

A study published in The BMJ found that women diagnosed with ductal carcinoma in situ (DCIS) outside of the NHS breast screening program are around four times as likely to develop invasive breast cancer and to die from breast cancer than women in the general population. This increased risk could last at least 25 years after diagnosis. The authors used data from the National Disease Registration Service to compare rates. They suggest regular checks for at least three decades. Opportunities for a more personalized risk-based approach to breast cancer screening might be possible, especially for younger women. These findings are relevant for the ongoing debate about overdiagnosis and overtreatment of DCIS and for the further development of personalized risk-based screening strategies.

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