A case series identified severe necrotic skin wounds associated with xylazine exposure in hospitalized adults, with 9% involving deep structures like bone or tendon. Researchers studied 29 patients with xylazine exposure and wound-related complaints, finding that 90% of wounds were on the arms and legs, with devitalized tissue in 60% of cases. They discovered that 87% of wounds occurred at drug injection sites, suggesting a link between xylazine and wound development. The study provides insight into wound characteristics related to xylazine exposure and may help in identifying and managing these wounds. Limitations include the study’s retrospective nature and potential recall bias.
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