A large randomized trial in the United States compared surgery with antibiotics for adults with appendicitis. Antibiotics were found to be noninferior based on 30-day health status. Seven out of 10 adults safely avoided appendectomy for 90 days with antibiotics, although this number dropped for patients with appendicoliths. Patients with appendicoliths were more likely to have a perforation if they underwent surgery. The study aimed to help patients make informed decisions about their treatment options. The results suggest that antibiotics may be a reasonable option for some patients, but not all. The COVID-19 pandemic has also influenced the discussion around treatment options.
Source link
Antibiotics Found Noninferior to Surgery In Randomized Appendicitis Trial
