Researchers have developed a new approach to identify kidney biomarkers for chronic kidney disease (CKD) progression. By combining 17 urine and plasma biomarkers, the study identified three health dimensions: systemic inflammation and filtration, tubular function, and tubular damage. These dimensions were associated with CKD progression and mortality risk, independent of clinical factors. This multi-biomarker approach offers potential for clarifying CKD progression in individuals with diabetes and monitoring response to medications. Further research is needed to determine the prognostic value of these kidney health dimensions for individual patients. The study was presented at ASN Kidney Week 2024.
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Researchers integrate multiple protein markers to predict health outcomes in individuals with chronic kidney disease
