A protein called CLEC14A, found on blood vessel cells in bone, has been identified to block the maturity of bone-forming cells, preventing them from forming bone tissue. Research led by Dr. Amy Naylor and Professor Roy Bicknell from the University of Birmingham found that when CLEC14A is present on endothelial cells, osteoblasts are unable to mature. This discovery could lead to potential treatments for conditions with insufficient bone formation, such as osteoporosis. Further research is needed to develop new treatment approaches for musculoskeletal conditions, including arthritis, where poor bone formation contributes to disability and pain.
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Protein blocking bone development could hold clues for future osteoporosis treatment
