Research presented at UEG Week 2024 shows that chronic stress disrupts the balance of gut microbiota, accelerating the progression of colorectal cancer (CRC). By eliminating certain gut bacteria and inducing stress, researchers identified a relationship between stress, gut microbiota, and CRC. They found that chronic stress reduces beneficial gut bacteria essential for a healthy immune response against cancer. Lactobacillus genus was highlighted as a potential therapeutic target. Supplementing mice with Lactobacillus during stress reduced tumor formation, indicating its role in enhancing anti-tumor immunity. The study suggests that restoring beneficial gut bacteria like Lactobacillus may play a critical role in cancer care, especially for patients facing chronic stress.
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Chronic stress accelerates colorectal cancer progression by disrupting the balance of gut microbiota, study shows
