Be Aware of Aspiration Risk With Anesthesia on GLP-1 RAs

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The European Medicines Agency has issued new recommendations for patients taking GLP-1 RAs who need general anesthesia or deep sedation. The EMA’s PRAC advised health professionals to consider the risk of delayed gastric emptying with GLP-1 RAs before administering anesthesia. GLP-1 RAs are used to treat type 2 diabetes and obesity by controlling blood sugar and reducing weight gain. Although delayed gastric emptying could increase the risk of aspiration during surgery, current evidence suggests that patients on GLP-1 RAs may only experience a modest delay in gastric emptying. Healthcare professionals and patients should be aware of this potential risk when undergoing procedures with general anesthesia or deep sedation.

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