Artificial intelligence has identified two plant-based bioactive compounds that could potentially serve as weight-loss drugs by activating the GLP-1R receptor. GLP-1 agonists have shown effectiveness in trials but come with side effects and the need for injection. AI was used to identify natural compounds that could activate GLP-1R without these drawbacks. Two plant-derived compounds, Compound A and Compound B, were found to bind strongly to key amino acids and are being further investigated for obesity treatment. This study demonstrates the potential of AI in drug discovery for therapeutic areas like GLP-1R agonists, although experimental validation is still needed.
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AI Identifies Two Natural Bioactive GLP-1 Compounds
