A new publication in Acta Materia Medica journal discusses the potential of neocryptolepine and its derivatives in cancer treatment. The article outlines the structures of 228 neocryptolepine derivatives, with some showing promising cytotoxic effects on cancer cells. The study highlights compounds that have good cytotoxicity against gastric and colorectal cancer cells, with potential mechanisms of action involving Topoisomerase II inhibition. The review provides important insights into the anti-cancer activities of neocryptolepine and its derivatives, offering a valuable reference for future drug development in the fight against cancer.
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Exploring the cytotoxic potential of neocryptolepine derivatives against cancer
