A triplet regimen was found to extend overall survival (OS) compared to the standard of care for patients with relapsed or refractory multiple myeloma in the phase 3 DREAMM-7 trial. The regimen consisted of belantamab mafodotin (Blenrep) plus bortezomib and dexamethasone (BVd). Results showed improved progression-free survival (PFS) and longer duration of response in the BVd group. An interim analysis also showed a statistically significant improvement in OS. The results were deemed clinically meaningful and potentially transformative for treatment. Complete data will be presented at the ASH Annual Meeting in December.
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