Breast cancer is a common malignancy, with genetic variants accounting for up to 10% of cases. A recent study led by Prof. Dina Schneidman-Duhovny has identified 80 genes that could significantly influence breast cancer risk, including 70 previously unknown genes. The study focused on families of Middle Eastern descent and found key roles for cellular pathways involving peroxisomes and mitochondria. The research utilized full genome sequencing and AI analysis, offering new insights into the genetic underpinnings of familial breast cancer. These findings may lead to targeted treatment strategies and specialized genetic testing panels, improving management and treatment outcomes for diverse patient populations.
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Study identifies 80 genes linked to increased risk of breast cancer
