New research using brain mapping tools suggests that Alzheimer’s disease damages the brain in two phases, with the first phase causing damage slowly and silently before symptoms appear, and the second phase causing more widespread damage in conjunction with symptoms. The study analyzed brains of 84 people and revealed that damage to inhibitory neurons in the early phase may trigger neural circuit problems. This new understanding of the disease may lead to the development of new treatments. The study utilized advanced genetic analysis tools to study changes in the middle temporal gyrus, a brain region vulnerable to Alzheimer’s, providing insight into the progression of the disease.
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Alzheimer’s disease may damage the brain in two phases
