Dr. Ray O’Connor reviews the latest clinical papers on breast cancer, the second leading cause of cancer death in the USA. Despite advances in treatment, breast cancer remains a significant global public health concern with high morbidity and mortality rates. Immunotherapy has emerged as a new therapeutic approach for certain patients, challenging the traditional view of breast cancer as immunologically unresponsive. The WHO Global Breast Cancer Initiative aims to reduce mortality rates by focusing on health promotion, timely diagnosis, and comprehensive treatment. Recommendations include personalized, high-value breast cancer care, survivorship programs, and evaluation of patient-reported outcomes. Advances in screening have increased detection rates, and ESMO guidelines provide comprehensive recommendations for breast cancer management. Breast cancer survivorship care emphasizes surveillance, healthy lifestyle, and psychosocial support.
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