The article highlights the importance of conducting rigorous systematic reviews on studies involving animals and cells to improve reproducibility, reduce animal use, and address potential pitfalls in research. The Cochrane organization popularized systematic reviews in clinical research, and researchers have adapted this approach for animal studies in recent years. The primer provides a comprehensive guide for performing systematic reviews of animal and in vitro research, helping researchers define research questions, conduct literature searches, assess evidence, synthesize data, and draw conclusions. By following this process, researchers can refine animal models, reduce animal use, and improve the quality of research and its reporting.
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Experts release the latest guide for systematic reviews of preclinical research
