Cognitive behavioral therapy enhances brain circuits to relieve depression

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Researchers at Stanford Medicine discovered that tailoring treatments for depression based on the type of depression a patient has can increase the likelihood of success. A study focused on adults with depression and obesity found that cognitive behavioral therapy focused on problem-solving led to a reduction in depression symptoms in a third of patients. This therapy also resulted in adaptive changes in brain circuitry, particularly in the cognitive control circuit. The study suggests that matching therapies with the neurological underpinnings of a patient’s depression can enhance treatment outcomes and pave the way for precision psychiatry.

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