In patients with heart failure and secondary mitral regurgitation, transcatheter edge-to-edge repair was found to be as effective as mitral valve surgery with fewer safety events in the MATTERHORN trial. The study included 210 patients who were randomly assigned to either undergo transcatheter edge-to-edge repair or surgical mitral valve repair or replacement. The primary efficacy endpoint showed no significant difference between the groups, while the primary safety outcome favored the transcatheter edge-to-edge repair group. These results suggest that transcatheter edge-to-edge repair may be a viable option for patients with secondary mitral regurgitation who are eligible for surgery.
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TEER noninferior to surgery in patients with heart failure, mitral regurgitation
