Comprehensive dataset from A4 study yields key insights about Alzheimer’s disease

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Data from the A4 study, the largest clinical trial of pre-symptomatic Alzheimer’s disease, is now available to researchers. The study involved screening over 7,500 individuals, enrolling 1,169 with pre-symptomatic Alzheimer’s, and collecting data for 4.5 years. Insights from the data include the link between amyloid buildup and cognitive decline. The data is shared through A4STUDYDATA.ORG for global research. The study also led to the development of a blood test for early amyloid detection. The release of this data is part of a long-standing commitment to open science and will inform future prevention trials in Alzheimer’s research.

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