Patients with advanced chronic kidney disease or end-stage kidney disease may experience more frequent episodes of hypoglycemia. Dialysis treatment can also affect blood glucose levels. Research suggests that patients with end-stage kidney disease, particularly young, Black, and female patients, are at higher risk for hypoglycemia. The kidneys play a more significant role in glucose regulation than previously thought, with the kidney’s ability to add glucose to circulation in various stress conditions. Continuous glucose monitoring is recommended for patients with advanced kidney disease to detect asymptomatic hypoglycemia and monitor glucose fluctuations for better management of the condition. Further studies are needed to evaluate optimal glucose sensing and treatment strategies for patients with diabetes and end-stage kidney disease.
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