A multicenter retrospective study in Australia evaluated 4109 sepsis patients from emergency departments to determine the impact of culture positivity on outcomes. Bacteremic, urine culture-negative patients had the highest risk for ICU admission and early representation post-discharge. Nonbacteremic, urine culture-positive patients had the longest hospital stays. Antibiotic administration before sample collection reduced the likelihood of positive culture results. Identifying nongenitourinary sepsis cases is crucial as they have a higher risk of adverse outcomes. The study highlights the importance of monitoring culture results, antibiotic appropriateness, and closer monitoring of bacteremic sepsis patients in hospitals. The study’s limitations include generalizability issues and potential unidentified confounders.
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Do Culture Results Influence Sepsis Outcomes in ED?
