‘Unhealthy’ gut microbiome patterns linked to heightened risk of death after organ transplant

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Research published in the journal Gut found that ‘unhealthy’ gut microbiome patterns are associated with a higher risk of death after solid organ transplants, particularly from cancer and infection. The study analyzed microbial patterns in fecal samples from transplant recipients in the Netherlands and found that deviations from the general population’s microbiome were linked to earlier deaths. Specific bacterial species, such as Clostridium and Hangatella, were associated with different causes of death. The researchers suggest that targeting the gut microbiome with therapies could improve patient outcomes, although more research is needed to establish causal links.

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