Scientists have identified more than 5,000 genetic variants that increase the risk of developing cancers such as eye, lung lining, brain, skin, and kidney cancers. The research focused on the BAP1 gene, a tumor protection gene, and found that disrupting variants in this gene significantly increase the risk of cancer. These findings, published in Nature Genetics, can help doctors diagnose patients and choose appropriate therapies. The study also revealed a link between harmful BAP1 variants and higher levels of IGF-1, a hormone associated with cancer growth. Early detection of these harmful variants can guide preventative measures and improve treatment outcomes.
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Scientists identify thousands of high-risk cancer gene variants
