Melasma is a complex skin condition influenced by genetics, hormones, and other factors. Common treatments include hydroquinone, retinoids, steroids, and triple combination cream. New treatments like azelaic acid, tranexamic acid, cysteamine, malassezin, methimazole, thiamidol, and 2-mercaptonicotinoyl glycine are proving effective. Laser treatments may be used for resistant cases. Education, skin exams, and pretreatment with tinted sunscreen are important. Combination therapy is often necessary, with topical therapy being the first line. Nanosecond and picosecond lasers can disperse melanin, and vascular lasers may be combined. Tranexamic acid may be used as a last resort. Clinical studies support the effectiveness and tolerability of these treatments.
Source link
Newer Therapies Target Different Melasma Components
