Higher levels of environmental metals in urine are linked to poorer cognitive function and an increased risk of dementia, according to a study of 6303 participants aged 45-84 from six US study centers. The study found associations between higher urinary concentrations of metals such as arsenic, cobalt, copper, uranium, and zinc with lower cognitive test scores. Individuals with higher levels of these metals had a 71% higher risk of dementia. The study suggests that metal exposure and levels in the body may be modifiable and could inform early screening and interventions for dementia prevention based on individual metal exposure and genetic profiles.
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